The early Saturday standalone game will be a battle of explosive offensive units with No. 1 Michigan facing No. 9 Saint Louis.
Both the Wolverines and Billikens topped 100 points in their opening-round matchups and will square off at 12:10 p.m. ET in what should be a high-scoring affair.
The second half of the doubleheader from Buffalo features No. 6 Louisville against No. 3 Michigan State, followed by the remainder of the day's matchups unfolding in a staggered schedule.
The Saturday finale will see No. 12 High Point, an early Cinderella, taking on John Calipari's No. 4 Arkansas at 9:45 p.m. ET.
Here's the full Round of 32 slate for Saturday.
Saturday tip times (all ET)
9 Saint Louis vs. 1 Michigan - 12:10 p.m.
6 Louisville vs. 3 Michigan State - 2:45 p.m.
9 TCU vs. 1 Duke - 5:15 p.m.
10 Texas A&M vs. 2 Houston - 6:10 p.m.
11 Texas vs. 3 Gonzaga - 7:10 p.m.
11 VCU vs. 3 Illinois - 7:50 p.m.
5 Vanderbilt vs. 4 Nebraska - 8:45 p.m.
12 High Point vs. 4 Arkansas - 9:45 p.m.
